Swati Basu PhD
Research Associate Professor
Department of Physics
Translational Science Center
Wake Forest Faculty Fellow
(Johnson Hall, WFU)
Lab: Kim-Shapiro labs, 205 Olin, 216 Olin
Office: 108C Olin
336 758 4988
One Week of Daily Dosing with Beetroot Juice Improves Submaximal Endurance and Blood Pressure in Older Patients with Heart Failure and Preserved Ejection Fraction. Joel Eggebeen, Daniel B. Kim-Shapiro, Mark Haykowsky, Timothy M. Morgan, Swati Basu, Peter Brubaker, Jack Rejeski, and Dalane W. Kitzman. JACC-Heart Failure. 2015
Interaction between the Haptoglobin 2 phenotype and Diabetes Mellitus on systolic pulmonary arterial pressure and nitrix oxide bioavailability in hemodialysis patients. Inbal Dahan, Evgeny Farber, Nadia Thauho, Nakhoul Nakhoul, Adi Francis, Mohamad Awawde, Andrew P Levy, Daniel Kim-Shapiro, Swati Basu, Farid Nakhoul. Journal of Diabetes Research, Vol 2015, p 1-7, 2015.
The relationship between plasma and salivary NOx. William H. Clodfelter, Swati Basu, Crystal Bolden, Patricia C. Dos Santos, S. Bruce King, Daniel B. Kim-Shapiro. Nitric Oxide, Vol.47, p 85-90. 2015.
Acute dietary nitrate supplementation does not augment submaximal forearm exercise hyperemia in healthy young men. Jin-Kwang Kim, David J Moore, David G Maurer, Daniel B Kim-Shapiro, Swati Basu, Michael P Flanagan, Ann Skulas-Ray, Penny Kris-Etherton, David N Proctor. Applied Physiology, Nutrition, and Metabolism, 40, 122-8, 2015.
Mechanisms of Human Erythrocytic Bioactivation of Nitrite. Chen Liu, Nadeem Wajih, Xiaohua Liu, Swati Basu, John Janes, Madison Marvel, Christian Keggi, Christine C. Helms, Amber N. Lee, Andrea M. Belanger, Debra I. Diz2, Paul J.Laurienti, David L. Caudell, Jun Wang, Mark T. Gladwin8, Daniel B. Kim-Shapiro. Journal of Biological Chemistry, 290, 1281–1294, 2015.
Dietary Nitrate Supplementation Improves Exercise Performance and Decreases Blood Pressure in COPD Patients (2014). Michael J Berry, Nicholas W Justus, Jordan I Hauser, Ashlee H Case, Christine C Helms, Swati Basu, Zachary Rogers, Marc T Lewis, Gary D Miller. Nitric Oxide: Biology and Chemistry. 2014.
Low NO concentration-dependence of the
reductive nitrosylation reaction of hemoglobin
Cytochrome c-mediated formation of
S-nitrosothiols in cells (2012).
Human neuroglobin functions as a redox regulated
nitrite reductase. (2011).
A novel role for cytochrome c:
An electron paramagnetic resonance study of the
affinity of nitrite for methemoglobin. (2010).
Rate of nitric oxide scavenging by hemoglobin
bound to haptoglobin. (2008).
Nitrite Reductase Activity of Cytochrome c.
Chemiluminescent Detection of S-nitrosated
Proteins: Comparison of the Tri-iodide, 3C and the modified 2C methods.
Rate of Nitric Oxide scavenging by hemoglobin bound to haptoglobin.
(2008). Nitric oxide: Biology and Chemistry. Vol. 18, 296-302. Ivan Azarov, Xiaojun He, Anne Jeffers, Swati Basu, Burak Ucer, Roy R Hantgan, Andrew Levy and Daniel B. Kim-Shapiro.
Nitrite reductase activity of hemoglobin S (Sickle) provides insight into contributions of heme redox potential versus ligand affinity.
(2008). Journal of Biological Chemistry. Vol 283 (6). 3628-3638. Rozalina Grubina, Swati Basu, Mauro Tiso, Daniel B. Kim-Shapiro and Mark T. Gladwin.
Catalytic generation of N2O3
by the concerted nitrite reductase and anhydrase activity of hemoglobin.
Concerted Nitric Oxide formation and Release
from the Simultaneous Reaction of Nitrite with Deoxy- and Oxyhemoglobin.
Hemoglobin effects in the Saville Assay.
Lack of allosterically controlled
intramolecular transfer of nitric oxide in hemoglobin.
Nitric oxide scavenging by red blood cells as a
function of hematocrit and oxygenation.
Interactions between auxin transport and the
actin cytoskeleton in developmental polarity of Fucus distichus embryos
in response to light and gravity.
Early embryo development in Fucus distichus
is auxin sensitive, (2002).
Chemical modification of essential arginine
residues associated with the red beet (Beta vulgaris L.) plasma membrane
Target Molecular size suggesting a dimeric
structure for the red beet plasma membrane Ca2+-ATPase (I995).
Characterization of red beet plasma membrane H+-ATPase
reconstituted in a planar paper bilayer system (1995).
Studies on the reaction mechanism and transport
function of P-type ATPases associated with the plant plasma membrane.
Salinity induced changes in leaf expansion,
photosynthesis and K+ accumulation in sunflower.
The adjustment of growth and K+
transport in Helianthus annus during salinization (1989).
PEER REVIEWED ABSTRACTS:
The Relationship Between Plasma and Salivary NOx (2014). William Clodfelter, Swati Basu, Crystal Bolden, Patricia DosSantos, Bruce King, Dany Kim-Shapiro. The Society for Free Radical Biology and Medicine’s Annual Meeting in Seattle, WA in November 2014.
Hemoglobin is the Primary Erythrocytic Nitrite Reductase (2014). Chen Liu, Xiaohua Liu, Nadeem Wajih, John Janes, Swati Basu, Madison Marvel, Christine Helms, Debra Diz, Paul Laurienti, David Caudell, Jun Wang, Mark T. Gladwin, and Daniel B. Kim-Shapiro. International Nitric Oxide Conference & 6th International Nitrite/Nitrate Conference. Cleveland, Ohio June 16-20, 2014.
Effects of iodide on
nitrite reduction by ascorbate and implications on nitrosamine formation
Nitrite reduction by
ascorbate is enhanced by iodide potentially mitigating nitrosamine formation
Activity of Cytochrome c.
Formation of Nitroso Compounds in the Reaction of Nitrite and Hemoglobin.
Swati Basu, Rozalina Grubina, Jinming Huang, Zhi
Huang, Anne Jeffers, Alice Jiang, Xiaojun He, Ivan Azarov, Ryan Seibert, Atul
Mehta, Rakesh Patel, Neil Hogg, S. Bruce King, Mark T. Gladwin, Daniel B.
chain antibody fusion protein selectively targets lipophilic substance to HER2
overexpressing breast carcinoma cells.
Effect of auxin
transport inhibitors on polarization of Fucus embryos in response to
light and gravity.
Auxin transport is
required for light-induced cell polarity and normal rhizoid development in Fucus
zygotes. S Basu, R. Luciano and G. K. Muday.
of the red beet plasma membrane Ca2+-ATPase by phenylglyoxal, 2, 3,
butanedione and diethylpyrocarbonate (1993).
Characterization of the
Ca2+-transporting ATPase of the plant plasma membrane using isolated
Salinity responses in growth and carbon metabolism in sunflower (1989). Supple. Plant Physiology 89:118. S. Basu and J. M. Cheeseman.
2013 Lab group
TSC BRJ study report 2013
Nitric Oxide Analyzer
Lab group 2008