Our research focuses on understanding how proteins work in the cell by studying the intricate relationships that exist between protein function and structure, involving communication networks both within the protein and between proteins. To achieve this we are developing methods and tools to aid in the early stages of drug discovery using Bioinformatics, Computational Biophysics and Systems Biology approaches.
For more information on general research interests of our group or current projects we are involved in please visit the Research or Projects pages. Additional research at Wake Forest University that is related to ours can be found on the Computational Biosciences and Molecular Signaling websites.
The Fetrow Group is excited to announce that we are beginning a new collaborative project with the Babbit Lab at the University of California, San Francisco (UCSF). As founders of the Structure-Function Linkage Database (SLFD) the Babbit Lab is devoted to the accurate classification of enzyme families based on the structure-function paradigm. Our group will be aiding in the development of a new automatic annotation process that utilizes the tools PASSS and DASP (developed by our group) to automatically classify enzyme families based on the structure-function paradigm. This effort will aid in the automatic population of the SFLD and will help to update current families more easily. More information about this collaborative research effort will be present on the Research page shortly.
The Arabidopsis 2010 Project grant "Flavonoid signaling and pathway modeling in Arabidopsis" was officialy funded as of May 1st, 2009! This is a collaborative research project between Virginia Tech and Wake Forest University (departments of Biology, Computer Science and Mathematics). To learn more about this grant please visit the Research page.