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Wake Forest University

Publications

    Invited Articles and Reviews

  1. Grabbing the cat by the tail: manipulating molecules one by one. Bustamante, C., Macosko, J.C., & Wuite, G.J.L. Nature Reviews Molecular and Cell Biology 1, 130-136 (2000).
  2. Outside the Business School, Teaching Entrepreneurship through Teams and Projects: Three Case Studies. Macosko J.C., Johnson A.D., & Yocum S.M., Edward Elgar Publishing ISBN: 978 1 84720 455 4 (August, 2009)

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    Peer-Reviewed Publications

  3. Kinesin velocity increases with the number of motors pulling a viscoelastic load. Gagliano JM, Walb MC, Blaker BD, Macosko JC & Holzwarth G. accepted in European Journal of Biophysics
  4. Selection of Bead-Displayed, PNA-encoded Chemicals. Gassman NR, Nelli JP, Dutta S, Kuhn AM, Bonin KD, Guthold M & Macosko JC accepted in Journal of Molecular Recognition
  5. In vivo Multimotor Force-Velocity Curves by Tracking and Sizing Sub-Diffraction Limited Vesicles. Shtridelman Y, Holzwarth GM, Bauer CT, Gassman NR, DeWitt DA & Macosko JC Cellular and Molecular Bioengineering, 2: 190-199 (2009)
  6. Structural and sequence analysis of fast evolving duplicated yeast genes indicates functional specialization with partially relaxed purifying selection. Turunen, O., Seelke, R., & Macosko, J.C. FEMS Yeast Res. 9: 16-31 (2009)
  7. The Genetic Code—more than just a table. Berleant D., White M., Pierce E., Tudoreanu E., Boeszoermenyi A., Shtridelman Y., and Macosko J.C. Cell Biochem Biophys, 55: 107-116(2009)
  8. Intraneuronal vesicular organelle transport changes with cell population density in vitro. Bauer CT, Shtridelman Y, Tome CM, Grim JQ, Turner CP,  Tytell M & Macosko JC Neurosci Lett 441: 173-177 (2008)
  9. Motion-enhanced, differential interference contrast (MEDIC) microscopy of moving vesicles in live cells: VE-DIC updated. Hill DB, Macosko JC & Holzwarth G J Microsc 231: 433-439 (2008)
  10. Force-Velocity Curves of Motor Proteins Cooperating In Vivo. Shtridelman Y, Cahyuti T, Townsend B, Dewitt D & Macosko JC Cell Biochem Biophys 52:19-29 (2008)
  11. Fewer active motors per vesicle may explain slowed vesicle transport in chick motoneurons after three days in vitro. Macosko, J.C., Newbern, J.M., Rockford, J., Chisena, E.N., Brown, C.M., Holzwarth, G., and Milligan C.E. Brain Research, In Press, Accepted Manuscript, Available online 20 March 2008
  12. Speckling Improves Tracking in Gliding Assays. Chisena, E.N. Wall, R.A., Macosko, J.C., and Holzwarth, G. Physical Biology, 4, 10-5 (2007)
  13. Stepping Statistics of Single HIV-1 Reverse Transcriptase Molecules during DNA Polymerization Ortiz, T.P., Marshall, J.A., Meyer, L.A., Davis, R.W., Macosko, J.C., Hatch, J., Keller, D.J. & Brozik, J.A. Journal of Physical Chemistry B 109,16127 – 16131 (2005)
  14. Closing of the Fingers Domain Generates Motor Forces in the HIV Reverse Transcriptase. Lu, H., Macosko, J.C., Habel-Rodriguez, D., Keller, R.W., Brozik, J.A. & Keller, D.J.  Journal Biological Chemistry 24, 54529-54532 (2004)
  15. Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization. Poirier, M.A., Li H., Macosko, J.C., Cai, S., Amzel, M., Ross, C.A., Journal of Biological Chemistry. 43, 41032-41037. (2002)
  16. The 1-127 HA2 construct of influenza virus hemagglutinin induces cell-cell hemifusion. Leikina E., LeDuc D.L., Macosko J.C. Epand, R., Epand, R., Shin ,Y.K., Chernomordik, L.V., Biochemistry 40, 8378-8386 (2001).
  17. 15N NMR study of the ionization properties of the influenza virus fusion peptide in zwitterionic phospholipid dispersions. Zhou Z., Macosko J.C., Hughes, D.W., Sayer, B.G., Hawes, J., Epand, R.M..Biophysical Journal 78, 2418-2425 (2000).
  18. A novel 5' displacement spin-labeling technique for electron paramagnetic resonance spectroscopy of RNA. Macosko, J.C., Pio, M.S., Tinoco, I. Jr, Shin, Y.K. RNA Journal 9, 1158-1166 (1999).
  19. The ectodomain of HA2 of influenza virus promotes rapid pH dependent membrane fusion. Epand, R.F., Macosko, J.C., Russell, C.J., Shin, Y.K., Epand, R.M., Journal of Molecular Biology 286, 489-503 (1999).
  20. The synaptic SNARE complex is a parallel four-stranded helical bundle. Poirier, M.A., Xiao, W., Macosko, J.C., Chan, C., Shin ,Y.K., Bennett, M.K., Nature Strucural. Biology 5, 765-769 (1998)
  21. The mechanism for low-pH-induced clustering of phospholipid vesicles carrying the HA2 ectodomain of influenza hemagglutinin. Kim, C.H., Macosko, J.C., & Shin, Y.-K. Biochemistry 37, 137-144 (1998)
  22. The membrane topology of the fusion peptide region of influenza hemagglutinin determined by spin-labeling EPR. Macosko, J.C., Kim, C.H., Shin. Y.K. Journal of Molecular Biology 267, 1139-1148 (1997)
  23. On the dynamics and conformation of the HA2 domain of the influenza virus hemagglutinin. Kim, C.H., Macosko, Yu, Y.G., Shin, Y.K., Biochemistry 35, 5359- 5365 (1996).

    24. Patents and Patent Applications

  24. Macosko, J.C. & Olsson, C., Centrifugal Force Molecular Sensor, UC Case No. B02-037.
  25. Macosko, J.C., Kim, C.-H., & Shin, Y.-K. Influenza Drug Target, UC Case No. B98-060.
  26. Macosko, J.C., Guthold, M., Lab-on-Bead™ encoding methods that enhance biological technologies, WFU No. 07-56

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