| ACS | Academic Computing Specialists (13 for the College + 1 Babcock) |
| ATG | Advanced Technology Group |
| BOT | Board of Trustees |
| CELI | Computer-Enhanced Learning Initiative (6) |
| CIT | Committee on Information Technology |
| IS | Information Systems (~82) |
| ISSC | Information Systems Support Center (Help Desk) |
| ITC | Information Technology Center (Library) |
| P2000/A2000 | Wake Forest Undergraduate Plan (The Plan for the Class 2000/Access 2000) |
| PPI | Productivity Point |
| RTA | Resident Technology Advisors (~20) |
| STARS | Student Technology AdvisoRS (~50) |
| TLC | Teaching and Learning Center |
| WSFCS | Winston-Salem/Forsyth County Schools |
| WFUSM/BGSM | WFU (Bowman Gray) School of Medicine (Hawthorne campus) |
| ICCEL | International Center for Computer Enhanced Learning |