Summary
Number of Different
Hydrogens
Every chemically distinct hydrogen or group of hydrogens will give a resonance
in the NMR spectra.
Integration
The area under the NMR resonance is proportional to the number of hydrogens
which that resonance represents. In this way, by measuring or integrating
the different NMR resonances, information regarding the relative numbers
of chemically distinct hydrogens can be found. Experimentally, the integrals
will appear as a line over the NMR spectrum.
Integration only gives
information on the relative number of different hydrogens, not the absolute
number.
Chemical Shift
Typical chemical shifts in proton nmr spectra
Structure
|
chemical
shift (ppm) |
RCH3
|
0.8 - 1.2 |
R2CH2
|
1.1 - 1.5 |
R3CH
|
~1.5 |
ArCH3
|
2.2 - 2.5 |
R2NCH3
|
2.2 - 2.6 |
R2CHOR
|
3.2 - 4.3 |
R2CHCl
|
3.5 - 3.7 |
RC(=O)CHR2
|
2.0 - 2.7 |
RCHCR=CR2
|
~1.7 |
RC=CH
|
4.9 - 5.9 |
ArH
|
6.0 - 8.0 |
RC(=O)H
|
9.4 - 10.4 |
RCCH
|
2.3 - 2.9 |
R2NH
|
2 - 4 |
ROH
|
1 - 6 |
ArOH
|
6 - 8 |
RCO2H
|
10 - 12 |
Splitting
NMR provides information on how many hydrogen neighbors exist for a particular
hydrogen or group of equivalent hydrogens. In general, an NMR resonance
will be split into N + 1 peaks where N = number of hydrogens
on the adjacent atom or atoms.
No.
of H's on the adjacent atoms
|
Splitting
pattern
|
0
|
a single peak,
a singlet |
1
|
split into two
peaks of equal size, a doublet |
2
|
three peaks with
an area in the ratio of 1:2:1, a triplet |
3
|
four peaks with
an area in the ratio of 1:3:3:1, a quartet |
|